DEVELOPMENT OF GAS CHROMATOGRAPHY FOR THE QUANTITATIVE DETERMINATION OF METHYLAMINE AND THIONYL CHLORIDE IN 4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE文献综述

 2022-12-19 19:39:36

AUTHOR: KABIR RUQAYYA MUHAMMAD

SUPERVISOR: LUO XUEFANG

INSTITUTE: CHINA PHARMACEUTICAL UNIVERSITY

TITLE: DEVELOPMENT OF GAS CHROMATOGRAPHY FOR THE QUANTITATIVE DETERMINATION OF METHYLAMINE AND THIONYL CHLORIDE IN 4-CHLORO-N-METHYL-2-PYRIDINECARBOXAMIDE

ABSTRACT:

Gas chromatography method with direct injection will be developed for the quantitative determination of the concentration (in ppm) of Methylamine and Thionyl Cl, respectively. Gas chromatography can be used for the direct separation and analysis of gaseous samples, liquid solutions, and volatile compounds. Gas chromatography is found to be the most suitable method of analysis due Methylamine and Thionyl Cl being volatile compounds. The analytical method (GC) will then be validated according ICH guidelines Q2[1]. Specificity and limits of detection and quantitation will be determined.

KEYWORDS:

4-chloro-N-methyl-2-pyridinecarboxamide, methylamine, thionyl chloride, GC method, validation, development, residual solvent

剩余内容已隐藏,您需要先支付 10元 才能查看该篇文章全部内容!立即支付

以上是毕业论文文献综述,课题毕业论文、任务书、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。