黄连黄芩配伍前后有效成分溶出率的变化文献综述

 2023-02-28 21:55:16

黄连黄芩研究进展摘 要:黄连和黄芩属于清热燥湿药,在临床上有良好的泻火解毒清热燥湿的作用。

黄连的主要成分是异喹啉类生物碱,以小檗碱为主,其次是巴马丁、黄连碱和表小檗碱等。

具有明显的抗病毒、抗肿瘤、抗炎、抗氧化、保护缺血心肌细胞和降血糖的作用,临床主要用于感染性疾病、糖尿病、高血压等症。

黄芩的化学成分包含黄酮类、萜类、酚酸类、苯乙醇、氨基酸、甾 醇、挥发油、多糖和微量元素等,在抗菌抗病毒、抗衰老、保肝等方面有显著地药理作用。

临床多用于子痫前期的肝脏保护、阿尔兹海默症和一些心血管疾病。

本文将从化学成分、提取工艺、指标性成分含量测定等方面对黄连和黄芩两味中药进行综述。

关键词:黄连、黄芩、化学成分、提取、药理RESEARCH PROGRESS OF COPTIS CHINENSIS AND SCUTELLARIA BAICALENSISYadie xu AbstractCoptis and scutellaria baicalensis are a kind of hot medicine, which has a good effect on detoxification. The main components of coptis are isoquinoline alkaloids, which are mainly berberine, followed by barmateen,berberine and berberine. It has obvious effects on anti-virus, anti-tumor, anti-inflammatory, anti-oxidative, ischemic cardiomyocytes and hypoglycemia, and is mainly used in infectious diseases, diabetes, hypertension, etc. The chemical composition of scutellariae are flavonoids, terpenoids, phenolic acids, phenylethyl alcohol glycosides, amino acids, alcohols, volatile oils, polysaccharides, and trace elements, etc. It has significant pharmacological effects on antibacterial antiviral, anti-aging, protect liver, etc. It is mainly used in liver protection, alzheimers disease and some cardiovascular diseases in pre-eclampsia. In this paper, we will review the traditional Chinese medicine of coptis and scutellaria from the aspects of chemical composition, extraction process, and determination of index components.Key words Coptis; Scutellaria baicalensis; chemical component; extract; pharmacology黄连最早记载于《神农本草经》,因为其根茎呈现黄色而得名黄连,药用部位是毛茛科植物黄连Coptis chinensis Franch.、三角叶黄连Coptis deltoidea C. Y. Cheng et Hsiao或云连Coptis teeta Wall.的干燥根茎。

以三种分别习称味连、雅连、云连。

而黄芩的药用品为唇形科植物黄芩Scutellaria baicalensis Georgi的干燥根。

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